Fluorescent imaging using a flatbed scanner

US9683938B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Aydogan Ozcan · Los Angeles, US
• Zoltan Gorocs · Los Angeles, US
• Yuye Ling · New York, US
• Meng Dai Yu · Auburn, US

Key dates

• Filing date: Jun 20, 2014
• Grant date: Jun 20, 2017
• Expiry date: Jun 20, 2034

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/101
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A scanning system for fluorescent imaging includes a sample holder configured to hold a sample therein, the sample holder defining a sample holding region. A scanner head spans the sample holding region and is movable relative to the sample holder. An array of light sources is disposed on an opposing side of the sample holder and is angled relative thereto. Respective controller are operably coupled to the scanner head and the array of light sources, wherein one controller selectively actuates a one or more rows of the array of light sources and another controller controls movement of the scanner head to capture fluorescent light emitted from within the sample holder in response to illumination from the actuated light sources. A filter designed to filter out scattered light from the sample may be interposed between the sample holder and the scanner head.