Patent · US Active

Selective EP4 receptor antagonistic substance for treatment of cancer

US9688674B2 · kind B2 · utility

4Cited by
8References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 19, 2014
Grant dateJun 27, 2017
Priority date
Expiry dateFeb 9, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D213/82
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention provides a medicament for the treatment of cancer, which cause a reduction of cancer. This invention relates to use of a compound which has inhibitory activities against prostaglandin E2 receptor (EP4 receptor) and is represented by the following general formula (I), (II), (III), or (IV), or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the compound or the salt for the manufacture of a medicament for the treatment of cancer. The invention relates to a method for treatment of cancer comprising administering the compound or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the compound or the salt to humans or animals. The compound or a pharmaceutically acceptable salt thereof, or the pharmaceutical composition may be used in combination with one or more second active agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.