Method of predicting survival time in myocardial infarction patients by measuring BAFF levels

US9688767B2 · kind B2 · utility

Assignees

• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
• UNIVERSITE DE PARIS DESCARTES · FR
• Université Pierre et Marie Curie · FR
• ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS (APHP) · FR

Inventors

• Ziad Mallat · Paris, FR
• Alain Tedgui · Paris, FR
• Tabassome Simon · Paris, FR
• Nicolas Danchin · Paris, FR

Key dates

• Filing date: Mar 14, 2014
• Grant date: Jun 27, 2017
• Expiry date: Mar 14, 2034

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/52
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a method for predicting the survival time of a patient suffering from myocardial infarction or the recurrence of a myocardial infarction. The method comprises the steps of i) determining the expression level of BAFF in a sample from the patient, ii) comparing the expression level with a predetermined reference value and iii) providing a good prognosis of the survival time or a low risk of the recurrence of a myocardial infarction when the expression level is lower than the predetermined reference value and a poor prognosis of the survival time or a high risk of the recurrence of a myocardial infarction when the expression level is higher than the predetermined reference value.