Patent · US Active

C-Met antibody combinations

US9688773B2 · kind B2 · utility

3Cited by

11References

20Claims

0Family size

Assignee

ARGEN-X N.V. · NL

Inventors

Anna Hultberg · Sint-Martens-Latem, BE
Michael John Scott Saunders · Wondelgem, BE
Johannes Joseph Wilhelmus De Haard · Vlaardingen, NL
Els Festjens · Zwevegem, BE
Natalie De Jonge · Zwijnaarde, BE
Paolo Michieli · L'Aquila, IT
Cristina Basilico · San Mauro Torinese, IT
Torsten Dreier · Breda, NL

Key dates

Filing date	Nov 3, 2011
Grant date	Jun 27, 2017
Priority date	—
Expiry date	Aug 16, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides a product combination or composition, and also multispecific antibodies comprising two or more antigen-binding sites (as antibodies or antigen binding fragments thereof), wherein two the antigen-binding bind to distinct non-overlapping epitopes of the human c-Met protein. The product combination or composition or multispecific antibody inhibits HGF-independent activation of the human c-Met receptor protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.