Aspartyl-tRNA synthetase-Fc conjugates
US9688978B2 · kind B2 · utility
23Cited by
75References
16Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 27, 2012 |
| Grant date | Jun 27, 2017 |
| Priority date | — |
| Expiry date | Jul 6, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides aspartyl-tRNA synthetase and Fc region conjugate polypeptides (DRS-Fc conjugates), such as DRS-Fc fusion proteins, compositions comprising the same, and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The DRS-Fc conjugates of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic and biological properties relative to corresponding, unmodified DRS polypeptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.