Aptamer-targetted antigen delivery
US9688991B2 · kind B2 · utility
18Cited by
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13Claims
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Assignee
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Key dates
| Filing date | Jul 3, 2013 |
| Grant date | Jun 27, 2017 |
| Priority date | — |
| Expiry date | Jul 3, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition is provided comprising an oligonucleotide aptamer conjugated to an antigen, wherein the aptamer is directed against a cell-surface target of an antigen-presenting cell. Also provided are methods of delivering an antigen to a dendritic cell and of eliciting an immune response in a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.