Surface treated staples, sutures and dental floss and methods of manufacturing the same

US9693841B2 · kind B2 · utility

Assignee

• ENSION INC. · US

Inventors

• Ali Hussain · Sialkot, PK
• Linda Cahalan · Cape Coral, US
• Greg Johnson · Boulder, US
• Mark J. Gartner · Wexford, US
• Patrick Cahalan · Maple Grove, US
• Brian J Fill · Pittsburgh, US
• Jeffrey W. Speakman · Butler, US

Key dates

• Filing date: Mar 14, 2014
• Grant date: Jul 4, 2017
• Expiry date: Sep 13, 2034

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B05D2258/00
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A variety of medical devices including staples sutures and dental floss with surface treatment on at least one tissue-facing surface to improve biologic function such as to control tissue adhesion are disclosed including heparin surface treatment which provides heparin present in an amount to yield heparin bioactivity of at least one of i) an ATIII binding of at least 2 pmol/cm2, and ii) a thrombin deactivation of at least 0.2 IU/cm2; an acrylic surface treatment for coupling thereto of a heparin surface treatment, a collagen surface treatment or both; and an amino-functional polysiloxane surface treatment for coupling thereto of a heparin surface treatment.