Aqueous formulations for coating microneedle arrays

US9693950B2 · kind B2 · utility

Assignee

• 3M INNOVATIVE PROPERTIES COMPANY · US

Inventors

• Amy S. Determan · Mahtomedi, US
• Peter R. Johnson · New York, US
• Joan T. Moseman · Lake Elmo, US
• Ryan T. Woldt · Minneapolis, US
• Kristen J. Hansen · Afton, US

Key dates

• Filing date: May 26, 2011
• Grant date: Jul 4, 2017
• Expiry date: Jan 23, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/26
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Aqueous formulations that include at least one active pharmaceutical ingredient; and at least one excipient, wherein the aqueous formulation has a viscosity of from 500 to 30,000 centipoise when measured at a shear rate of 100 s−1 and a temperature of 25° C.; a surface tension that is not greater than 60 dynes/cm when measured under ambient conditions; or a contact angle on a medical grade polymeric material of 50° or greater when measured under ambient conditions. Methods of coating and coated microneedle arrays using the aqueous formulations are also disclosed herein.