Production of midbrain dopaminergic neurons and methods for the use thereof
US9694036B2 · kind B2 · utility
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Key dates
| Filing date | Mar 20, 2015 |
| Grant date | Jul 4, 2017 |
| Priority date | — |
| Expiry date | Mar 20, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4706
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.