Methods of treatment of a neurological disorder using electrical nerve conduction block

US9694181B2 · kind B2 · utility

Assignee

• CASE WESTERN RESERVE UNIVERSITY · US

Inventors

• Niloy Bhadra · Cleveland Heights, US
• Narendra Bhadra · Chesterland, US
• Kevin L. Kilgore · Cleveland, US
• Scott Lempka · Cleveland, US
• Jesse Wainright · Willoughby Hills, US
• Tina Vrabec · Willoughby Hills, US
• Manfred Franke · Valencia, US

Key dates

• Filing date: Dec 15, 2015
• Grant date: Jul 4, 2017
• Expiry date: Dec 15, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N1/36171
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Described herein are methods of treating various neurological disorders using electrical nerve conduction block (ENCB) without causing electrochemical damage. Examples of the various neurological disorders can include pain, muscle spasticity, hyperhidrosis, vertigo, sialorrhea, or the like. The methods can include placing an electrode contact in electrical communication with a nerve that transmits a signal related to the neurological disorder. The method also includes applying an ENCB to the nerve through the electrode contact. The electrode contact can include a high charge capacity material that prevents formation of damaging electrochemical reaction products at a charge delivered by the ENCB. The method also includes blocking transmission of the signal related to the neurological disorder through the nerve with the ENCB to treat the neurological disorder.