Two-dimensional fluid separation with controlled pressure

US9694301B2 · kind B2 · utility

Assignee

• AGILENT TECHNOLOGIES, INC. · US

Inventors

• Konstantin Choikhet · Karlsruhe, DE
• Klaus Witt · Keltern, DE

Key dates

• Filing date: May 10, 2012
• Grant date: Jul 4, 2017
• Expiry date: May 10, 2032

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2030/328
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A sample separation apparatus for separating a liquid sample includes a first separation unit for separating the sample, a first fluid drive for conducting the sample to be separated through the first separation unit, a second separation unit, arranged downstream of the first separation unit, for further separating the sample, a second fluid drive for at least partially conducting the sample through the second separation unit, and a fluidic valve having interfaces fluidically coupled to the first and second fluid drives and being switchable for performing the separation of the sample. The apparatus is configured for adjusting a pressure at a predefined position to a predefined value, wherein the predefined position is in a fluidic path between an outlet of the first separation unit and an inlet of the second separation unit or in fluid communication with this fluidic path.