Method for production of reprogrammed cell using chromosomally unintegrated virus vector
US9695445B2 · kind B2 · utility
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2References
10Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 29, 2015 |
| Grant date | Jul 4, 2017 |
| Priority date | — |
| Expiry date | Jul 29, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/18843
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An objective of the present invention is to provide vectors for conveniently and efficiently producing ES-like cells in which foreign genes are not integrated into the chromosome. The present inventors discovered methods for producing ES-like cells from somatic cells using chromosomally non-integrating viral vectors. Since no foreign gene is integrated into the chromosome of the produced ES-like cells, they are advantageous in tests and research, and immunological rejection and ethical problems can be avoided in disease treatments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.