Patent · US Active

Difluorolactam compositions for EP4-mediated osteo related diseases and conditions

US9701630B2 · kind B2 · utility

2Cited by

27References

20Claims

0Family size

Assignees

CAYMAN CHEMICAL COMPANY, INC. · US
MYOMETRICS LLC · US

Inventors

Stephen Douglas Barrett · Hartland, US
Fred Lawrence Ciske · Dexter, US
Joseph Michael Colombo · Ann Arbor, US
Gregory William Endres · Saline, US
Bradlee David Germain · Ann Arbor, US
Andriy Kornilov · Ypsilanti, US
James Bernard Kramer · Sylvania, US
Adam Uzieblo · Farmington Hills, US
Thomas Allen Owen · Pequannock, US
James Paul O'Malley · Dunedin, NZ

Key dates

Filing date	Aug 2, 2016
Grant date	Jul 11, 2017
Priority date	—
Expiry date	Aug 2, 2036

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61L2430/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are compositions and methods of treating osteroporosis, bone fracture, bone loss, and increasing bone density by administration of compounds of formula (I)or compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier, wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.