Polypeptides specifically binding to IL-23

US9701717B2 · kind B2 · utility

Assignee

• COMPLIX NV · BE

Inventors

• Johan Desmet · Kortrijk, BE
• Maria Henderikx · Hasselt, BE
• Klaartje Somers · Kortessem, BE
• Stefan Loverix · Ternat, BE
• Mark Vaeck · Zemst, BE
• Ignace Lasters · Ekeren, BE

Key dates

• Filing date: Oct 22, 2013
• Grant date: Jul 11, 2017
• Expiry date: Oct 22, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2318/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The application provides Alphabodies that specifically bind to IL-23, as well as to polypeptides that comprise or essentially consist of such Alphabodies. Also provided herein are nucleic acids encoding such Alphabodies; to methods for preparing such Alphabodies and polypeptides; and in particular to pharmaceutical compositions, that comprise such Alphabodies, polypeptides, nucleic acids and/or host cells.