Patent · US Active

Humanized antibody or fragment thereof specific for CD45R0

US9701756B2 · kind B2 · utility

0Cited by

1References

4Claims

0Family size

Assignee

Miltenyi Biotec, Inc. · DE

Inventors

Holger Thie · Biberach, DE
Stefan Tomiuk · Neunburg vorm Wald, DE
Iris Bürger · Rösrath, DE
Volker Nolle · Kürten, DE

Key dates

Filing date	Nov 25, 2015
Grant date	Jul 11, 2017
Priority date	—
Expiry date	Nov 25, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides a humanized antibody or fragment thereof specific for the antigen CD45R0, wherein said antibody or fragment thereof comprises a humanized heavy chain variable domain comprising a CDR1 region of SEQ ID NO:1, a CDR2 region of SEQ ID NO:2, and a CDR3 region of SEQ ID NO:3, and a humanized light chain variable domain comprising a CDR1 region of SEQ ID NO:4, a CDR2 region of SEQ ID NO:5, and a CDR3 region of SEQ ID NO:6. It is also provided the use of the present antibody or fragment thereof for enrichment or depletion of CD45R0-expressing cells from a sample comprising CD45R0-expressing cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.