Test cartridge for use in rapid analysis of biological samples

US9701995B2 · kind B2 · utility

Assignee

• Fundamental Solutions Corporation · US

Inventors

• Marvin R. Williams · Easton, US
• Charles McBrairty · Easton, US
• Daniel W. Pfautz · Hatfield, US
• Thomas Joel Zupancic · Worthington, US
• Lingchun ZENG · Columbus, US
• Andrew Weiman · Langhorne, US
• Richard S. Brody · Worthington, US
• Joseph D. Kittle · Houston, US
• Anthony Truscott · San Diego, US
• Robert Baranowski · San Diego, US

Key dates

• Filing date: Mar 26, 2015
• Grant date: Jul 11, 2017
• Expiry date: Oct 27, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/0221
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A test cartridge for use in sample analysis is provided. The test cartridge includes a reservoir card that further includes a reagent that includes living biological cells; and a test cartridge base configured to accept the reservoir card. The reservoir card is configured to interface with a test cartridge base through at least one fluid port. The test cartridge base includes an elliptical reaction chamber having a central axis and an inlet channel connected to the reaction chamber. The inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal and is offset from the central axis of the reaction chamber. Upon introducing a sample to be analyzed into the test cartridge base through the inlet channel, the sample is homogeneously mixed with the reagent while minimizing damage to the living biological cells.