Method and system for magnetic resonance imaging using nitrogen-vacancy centers

US9702900B2 · kind B2 · utility

Assignees

• President and Fellows of Harvard College · US
• University College London · GB

Inventors

• Amir Yacoby · Cambridge, US
• Michael S. Grinolds · Somerville, US
• Marc Warner · Eagle, US
• Kristiaan De Greve · Cambridge, US
• Yuliya Dovzhenko · Cambridge, US

Key dates

• Filing date: May 26, 2015
• Grant date: Jul 11, 2017
• Expiry date: Dec 1, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01R33/62
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method for performing sub-nanometer three-dimensional magnetic resonance imaging of a sample under ambient conditions using a diamond having at least one shallowly planted nitrogen-vacancy (NV) center. A driving radio-frequency (RF) signal and a microwave signal are applied to provide independent control of the NV spin and the target dark spins. A magnetic-field gradient is applied to the sample with a scanning magnetic tip to provide a narrow spatial volume in which the target dark electronic spins are on resonance with the driving RF field. The sample is controllably scanned by moving the magnetic tip to systematically bring non-resonant target dark spins into resonance with RF signal. The dark spins are measured and mapped by detecting magnetic resonance of said nitrogen-vacancy center at each of said different magnetic tip positions. The dark-spin point-spread-function for imaging the dark spins is directly measured by the NV center.