Systems and methods for corneal cross-linking with pulsed light
US9707126B2 · kind B2 · utility
15Cited by
79References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 31, 2012 |
| Grant date | Jul 18, 2017 |
| Priority date | — |
| Expiry date | Mar 10, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2009/00872
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for controlling activation of Riboflavin applied to an eye includes applying the Riboflavin to a selected region of a cornea of the eye and initiating cross-linking activity in the selected region by activating the Riboflavin with pulsed light illumination. The pulsed light illumination has an irradiance, dose, and an on/off duty cycle. The irradiance, the dose, and the on/off duty cycle are adjusted in response to a determination of photochemical kinetic pathways for Riboflavin cross-linking activity and to control photochemical efficiency.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.