Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients

US9707155B2 · kind B2 · utility

Assignee

• CORNING INCORPORATED · US

Inventors

• Wendell Porter Weeks · Corning, US
• Robert Anthony Schaut · Corning, US
• Steven Edward DeMartino · Corning, US
• John Stephen Peanasky · Big Flats, US

Key dates

• Filing date: Apr 23, 2014
• Grant date: Jul 18, 2017
• Expiry date: Oct 28, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, LYXUMIA (lixisenatide), LEMTRADA (alemtuzumab), REGN727/SAR236553 (alirocumab), SAR2405550/BSI-201 (iniparib), OTAMIXABAN (otamixaban), SARILUMAB (sarilumab), LANTUS and LYXUMIA (insulin glargine and lixisenatide) or VISAMERIN/MULSEVO (semuloparin sodium).