Hydrophobically modified antisense oligonucleotides comprising a triple alkyl chain
US9707250B2 · kind B2 · utility
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Key dates
| Filing date | Jun 5, 2014 |
| Grant date | Jul 18, 2017 |
| Priority date | — |
| Expiry date | Jun 5, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2330/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns an oligonucleotide modified by substitution at the 3′ or the 5′ end by a moiety comprising at least three saturated or unsaturated, linear or branched hydrocarbon chains comprising from 2 to 30 carbon atoms, and the use therefore as a medicament, in particular for use for treating cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.