Benzimidazole derivatives and preparation process and pharmaceutical uses thereof
US9708306B2 · kind B2 · utility
3Cited by
1References
22Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Mar 18, 2015 |
| Grant date | Jul 18, 2017 |
| Priority date | — |
| Expiry date | Mar 18, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention belongs to the technical field of pharmaceutical chemistry, and particularly pertains to benzimidazole derivatives, and preparation process and pharmaceutical uses thereof. Benzimidazole derivatives include Ligustrazine and NO donor derivatives. The kind of the compounds can rapidly release Ligustrazine or No in vivo, so that they can produce effective synergetic effects with Azilsartan, to enhance the anti-hypertension effect, and reduce adverse effects, and the released Ligustrazine can produce ideal protection to patients' livers and kidneys, thereby filling blanks in the prior art.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.