Patent · US Active

Spiro-quinazolinone derivatives and their use as positive allosteric modulators of mGluR4

US9708321B2 · kind B2 · utility

0Cited by

5References

21Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Nadia Brugger · Cambridge, US
Brian L. Hodous · Cambridge, US
Amanda E. Sutton · Hingham, US
Justin Potnick · Acton, US
Theresa L. Johnson · Salem, US
Thomas E. Richardson · Durham, US
Thomas Francis Nelson Haxell · Morrisville, US
James M. Dorsey · Havertown, US
Robert James Foglesong · Durham, US

Key dates

Filing date	Jan 23, 2014
Grant date	Jul 18, 2017
Priority date	—
Expiry date	Jan 23, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D498/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to novel spiro-quinazolinone derivatives as positive allosteric modulators for modulating metabotropic glutamate receptor subtype 4 (mGluR4) and/or altering glutamate level or glutamatergic signalling.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.