Aryl amide-based kinase inhibitors

US9708337B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Vivekananda M. Vrudhula · Killingworth, US
• Carolyn Diane Dzierba · Middletown, US
• Joanne J. Bronson · Madison, US
• John E. Macor · Guilford, US
• Susheel Jethanand Nara · Mumbai, IN
• Ramkumar Rajamani · Wallingford, US
• Maheswaran Sivasamban Karatholuvhu · Chennai, IN

Key dates

• Filing date: Feb 6, 2014
• Grant date: Jul 18, 2017
• Expiry date: Feb 12, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.