Compositions for regulating iron homeostasis and methods of using same

US9708379B2 · kind B2 · utility

Assignees

• The General Hospital Corporation · US
• FERRUMAX CORPORATION · US

Inventors

• Herbert Y. Lin · Watertown, US
• Jodie Babitt · Newton, US
• Tracey Menhall · Boston, US
• Patrick Gearing · Seattle, US

Key dates

• Filing date: Jan 19, 2012
• Grant date: Jul 18, 2017
• Expiry date: Apr 25, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to hemojuvelin-IgG Fc domain fusion proteins, variants, derivatives, fragments and peptide mimetics derived therefrom and methods of using these fusion proteins for the regulation of iron homeostasis and the treatment of diseases related to iron homeostasis.