Methods for producing a population of pancreatic beta-cells
US9708608B2 · kind B2 · utility
1Cited by
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7Claims
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Key dates
| Filing date | Sep 16, 2013 |
| Grant date | Jul 18, 2017 |
| Priority date | — |
| Expiry date | Sep 16, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/845
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an in vitro or ex vivo method for producing a population of pancreatic beta-cells, comprising the step of inhibiting the expression or the activity of Arx in a population of pancreatic alpha-cells. The present invention also relates to method for inducing the conversion of pancreatic alpha-cells in pancreatic beta-cells in a patient in need thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.