Method and system for in vivo hydrogen peroxide detection with ultrasound
US9713459B2 · kind B2 · utility
1Cited by
3References
28Claims
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Key dates
| Filing date | Jun 11, 2013 |
| Grant date | Jul 25, 2017 |
| Priority date | — |
| Expiry date | Aug 15, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2250/0096
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and system are provided for detection of localized hydrogen peroxide within tissue by introducing a catalase-containing material into at location of interest, positioning an ultrasound transducer over the location, and generating an ultrasound image to detect microbubbles, where the presence of microbubbles indicate the presence of localized hydrogen peroxide. The catalase-coated surface may be the inner surface of a microtube, on the surface of or incorporated within a nanosphere or microsphere, or an implantable device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.