Method for producing 2-amino-6-methylnicotinic acid
US9714223B2 · kind B2 · utility
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Key dates
| Filing date | Jun 27, 2014 |
| Grant date | Jul 25, 2017 |
| Priority date | — |
| Expiry date | Jun 27, 2034 |
Classification
- Technology area (CPC —)General
Abstract
The present invention provides a method for producing 2-amino-6-methylnicotinic acid represented by formula [I], wherein the production method comprises: (a) reacting 2-chloro-3-cyano-6-methylpyridine represented by formula [II] in an ammonia aqueous solution to obtain a reaction solution containing 2-amino-6-methylnicotinamide represented by formula [III]; and (b) removing the ammonia from the reaction solution, then reacting the 2-amino-6-methylnicotinamide represented by formula [III]with a base to produce 2-amino-6-methylnicotinic acid represented by formula [I].
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