Therapeutically active pyrazolo-pyrimidine derivatives

US9714248B2 · kind B2 · utility

Inventors

• Daniel James Ford · San Francisco, US
• Richard Jeremy Franklin · Wokingham, GB
• Anant Ramrao Ghawalkar · Hyderabad, IN
• Helen Tracey Horsley · Slough, GB
• Qiuya Huang · Leuven, BE
• James Thomas Reuberson · Slough, GB
• Bart Vanderhoydonck · Diest, BE

Key dates

• Filing date: Dec 20, 2013
• Grant date: Jul 25, 2017
• Expiry date: Jan 15, 2034

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A series of pyrazolo[3,4-d]pyrimidine derivatives that are substituted at the 4-position by a diaza monocyclic, bridged bicyclic or spirocyclic moiety, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases and malaria; and organ and cell transplant rejection.