Cortistatin analogues and syntheses thereof
US9714255B2 · kind B2 · utility
1Cited by
16References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 8, 2015 |
| Grant date | Jul 25, 2017 |
| Priority date | — |
| Expiry date | Sep 8, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to analogs of cortistatin A, J, K, and L, having the general formula:and salts thereof, wherein R1, R2, R3, R4, n, and m are as defined herein; processes for preparing such compounds and intermediates thereto; pharmaceutical compositions comprising such compounds; methods for treating a proliferative disease; methods for treating a disease associated with aberrant angiogenesis; methods for inhibiting angiogenesis; and processes for preparing cortistatin A, J, K, and L, and analogs thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.