PEGylated tyrosyl-tRNA synthetase polypeptides
US9714419B2 · kind B2 · utility
0Cited by
80References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 8, 2012 |
| Grant date | Jul 25, 2017 |
| Priority date | — |
| Expiry date | Oct 2, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides PEGylated tyrosyl-tRNA synthetase (YRS) polypeptides, compositions comprising the same, and methods of using such polypeptides and compositions for treating or diagnosing a variety of conditions. The PEGylated YRS polypeptides of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic properties compared to non-PEGylated YRS polypeptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.