Production of stable non-polyadenylated RNAs
US9717749B2 · kind B2 · utility
1Cited by
1References
21Claims
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Key dates
| Filing date | Oct 16, 2013 |
| Grant date | Aug 1, 2017 |
| Priority date | — |
| Expiry date | Oct 16, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates in aspects to hybrid RNAs lacking a poly-A tail and nucleic acid vectors for expressing the RNA. The hybrid RNAs in some instances have a 3′ terminal stabilizing triple helical structure. Related methods for expressing said RNAs in vivo and in vitro are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.