Process for preparation of optically pure N-substituted-3-methoxypropionic acid derivatives
US9718765B1 · kind B1 · utility
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20Claims
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Key dates
| Filing date | Jun 21, 2016 |
| Grant date | Aug 1, 2017 |
| Priority date | — |
| Expiry date | Jun 21, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method of producing optically pure N-substituted-3-methoxy propionic acid is provided, which includes the steps of: with a chiral amine in a solvent to obtain a diastereomeric salt represented by formula (IV): wherein R1 is selected from the group consisting of C1-5 alkyl, C1-6 alkoxy and C6-10 aryloxy group, and R2 is selected from the group consisting of C2-5 alkyl, C6-8 cycloalkyl and C6-10 aryl.
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