Patent · US Active

Macrocyclic compounds as Trk kinase inhibitors

US9718822B2 · kind B2 · utility

22Cited by
35References
15Claims
0Family size

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Key dates

Filing dateJan 9, 2017
Grant dateAug 1, 2017
Priority date
Expiry dateJan 9, 2037

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein ring A, ring B, W, m, D, R2, R2a, R3, R3a, and Z are as defined herein, are inhibitors of Trk kinases and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.