Patent · US Active

2, 6-Di-nitrogen-containing substituted purine derivative, and preparation method, pharmaceutical composition and use thereof

US9718823B2 · kind B2 · utility

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12Claims

0Family size

Assignee

Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory · CN

Inventors

Guofeng Wu · 安丰镇, CN
Yongmei Xu · Durham, US
Wei Mao · Chengdu, CN
Chunlin Chen · Xinchang County, CN
Zhanggui Wu · Brookline, US
Xiaoqin Lin · Haifeng, CN
Jun Wang · Nanjing, CN
Jinna Cai · Xinchang County, CN
Sen Xiao · Xinchang County, CN
Lili Lv · Xinchang County, CN

Key dates

Filing date	Aug 27, 2014
Grant date	Aug 1, 2017
Priority date	—
Expiry date	Aug 27, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D473/16
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a 2, 6-di-nitrogen-containing substituted purine derivative having a formula (I) structure, or pharmaceutical salt or hydrate thereof, and preparation method and use thereof. The compound is broad spectrum anticancer, low toxicity, high anticancer activity and good stability.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.