Artificial antigen of aflatoxin biosynthetic precursor sterigmatocystin and method for preparing same
US9718836B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 24, 2015 |
| Grant date | Aug 1, 2017 |
| Priority date | — |
| Expiry date | May 12, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/0002
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An artificial antigen of aflatoxin biosynthetic precursor Sterigmatocystin (ST) and a method for preparing same. Firstly, hydroxyacetic acid is reacted with the double bound of the difuran ring in the aflatoxin biosynthetic precursor ST, yielding an aflatoxin biosynthetic precursor ST hapten with an active carboxymethoxy group. Secondly, a carboxyl group on the ST hapten is attached to an amino group on a carrier protein. At last, the artificial antigen of aflatoxin biosynthetic precursor ST is obtained by dialysis and lyophilize.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.