Patent · US Active

Artificial antigen of aflatoxin biosynthetic precursor sterigmatocystin and method for preparing same

US9718836B2 · kind B2 · utility

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Key dates

Filing dateMar 24, 2015
Grant dateAug 1, 2017
Priority date
Expiry dateMay 12, 2035

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K39/0002
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An artificial antigen of aflatoxin biosynthetic precursor Sterigmatocystin (ST) and a method for preparing same. Firstly, hydroxyacetic acid is reacted with the double bound of the difuran ring in the aflatoxin biosynthetic precursor ST, yielding an aflatoxin biosynthetic precursor ST hapten with an active carboxymethoxy group. Secondly, a carboxyl group on the ST hapten is attached to an amino group on a carrier protein. At last, the artificial antigen of aflatoxin biosynthetic precursor ST is obtained by dialysis and lyophilize.

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