Substituted pyrimidines for treatment of a cough selected from chronic pathological cough, sub-acute pathological cough, acute pathological cough, neuronal hypersensitivity underlying chronic cough, neuronal hypersensitivity underlying sub-acute cough and neuronal hypersensitivity underlying acute cough
US9724346B2 · kind B2 · utility
2Cited by
6References
15Claims
0Family size
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Key dates
| Filing date | Feb 2, 2016 |
| Grant date | Aug 8, 2017 |
| Priority date | — |
| Expiry date | Feb 2, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for treating cough, chronic cough and urges to cough associated with respiratory diseases with a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of Formula (I):or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are as defined herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.