Spray-drying process
US9724664B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 19, 2010 |
| Grant date | Aug 8, 2017 |
| Priority date | — |
| Expiry date | Mar 19, 2030 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2/04
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The process comprises delivering a spray solution comprising an active agent and a matrix material in an organic solvent to a spray-drying apparatus, atomizing the spray solution into droplets within the spray-drying apparatus to remove at least a portion of the organic solvent from the droplets to form a plurality of particles, and collecting the particles. The spray solution may be formed by forming a feed suspension comprising the active agent, the matrix material, and the organic solvent, wherein the feed suspension is at a temperature T1, and directing the feed suspension to a heat exchanger, thereby increasing the temperature of the feed suspension to a temperature T2, wherein T2 is greater than T1, and the spray solution is at a pressure greater than the vapor pressure of the organic solvent at T2, such that the active agent and matrix material are soluble in the organic solvent at T2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.