3-oxo-tetrahydro-furo[3,2-B]pyrrol-4(5H)-yl) derivatives I

US9725459B2 · kind B2 · utility

Assignee

• GRUNENTHAL GMBH · DE

Inventors

• Antonio Nardi · Gambellara, IT
• Paul Ratcliffe · Lanark, GB
• Tobias Craan · Niedernberg, DE
• Torsten Hertrampf
• Bernhard Lesch · Aachen, DE
• Robert Kime · Stolberg, DE
• Henning Steinhagen · Pocking, DE

Key dates

• Filing date: Apr 23, 2015
• Grant date: Aug 8, 2017
• Expiry date: Apr 23, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to amidic oxotetrahydro-2H-furo[3.2-b]pyrrol-4(5H)-yl) derivatives as dual CatS/K inhibitors. to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.