CD27 single chain molecules and encoding nucleic acids

US9725495B2 · kind B2 · utility

Assignee

• APOGENIX AG · DE

Inventors

• Oliver Hill · Neckarsteinach, DE
• Christian Gieffers · Dossenheim, DE
• Meinolf Thiemann · Schriesheim, DE

Key dates

• Filing date: Jun 3, 2016
• Grant date: Aug 8, 2017
• Expiry date: Jun 3, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/35
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention refers to single-chain fusion proteins comprising three soluble TNF superfamily (TNFSF) cytokine domains and nucleic acid molecules encoding these fusion proteins. The fusion proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.