Non-ionic, low osmolar contrast agents for delivery of antisense oligonucleotides and treatment of disease
US9725716B2 · kind B2 · utility
10Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 6, 2012 |
| Grant date | Aug 8, 2017 |
| Priority date | — |
| Expiry date | Jan 27, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compositions comprising an antisense oligonucleotide and a non-ionic, low-osmolar contrast agent. Also disclosed are methods of delivering an antisense oligonucleotide to a target sire comprising incorporating the antisense oligonucleotide into a composition comprising a non-ionic, low-osmolar contrast agent. Also disclosed are methods of treating a neurodegenerative disease comprising administering one or more of the compositions disclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.