Substituted aminoimidazopyridazines

US9730929B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Knut Eis · Berlin, DE
• Florian Pühler · Berlin, DE
• Ludwig Zorn · Berlin, DE
• Arne Scholz · Berlin, DE
• Philip Lienau · Berlin, DE
• Mark Jean Gnoth · Mettmann, DE
• Ulf Bömer · Glienicke, DE
• Judith Günther · Berlin, DE
• Jörg Fanghänel · Berlin, DE
• Daniel Korr · Berlin, DE

Key dates

• Filing date: May 30, 2012
• Grant date: Aug 15, 2017
• Expiry date: Oct 29, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to substituted aminoimidazopyridazine compounds of general formula (I): in which A, R1, R2, R3 and R4 are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.