Patent · US Active

PRMT5 inhibitors and uses thereof

US9732072B2 · kind B2 · utility

16Cited by
51References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 14, 2015
Grant dateAug 15, 2017
Priority date
Expiry dateOct 14, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D407/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.