Engineered craniofacial constructs with composite scaffold

US9732321B2 · kind B2 · utility

Assignees

• The General Hospital Corporation · US
• Massachusetts Eye and Ear Infirmary · US

Inventors

• Erik Bassett · Watertown, US
• Mack Cheney · Brookline, US
• Theresa A. Hadlock · Arlington, US
• Irina Pomerantseva · Wakefield, US
• Mark Randolph · Chelmsford, US
• Cathryn Sundback · Harvard, US
• Joseph P. Vacanti · Winchester, US

Key dates

• Filing date: Feb 16, 2011
• Grant date: Aug 15, 2017
• Expiry date: Jun 7, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/54
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The present invention provides for compositions and constructs for craniofacial reconstruction implants, and methods for making and using same. Specific embodiments provide for a biocompatible scaffold having an auricular shape and a permanent bendable framework within the scaffold, wherein the permanent bendable framework allows deformation and return to pre-deformation shape, and thus maintains the auricular shape of the scaffold.