Patent · US Active

Compositions for mesoderm derived ISL1+ multipotent cells (IMPs), epicardial progenitor cells (EPCs) and multipotent C56C cells (C56Cs) and methods of producing and using same

US9732322B2 · kind B2 · utility

2Cited by
18References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 10, 2015
Grant dateAug 15, 2017
Priority date
Expiry dateDec 10, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2533/90
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to inter alia, methods for the generation and maintenance of Mesoderm-derived ISL1+ Multipotent Progenitors (IMPs), the production of a number of pluripotent cells including and epicardial pluripotent cells (EPCs) and using these cells to produce endothelial cells, cardiomyocytes, smooth muscle cells, vascular cells and other cells and related methods as otherwise disclosed herein. The invention also relates to compositions comprising a population of cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.