Segmented micro RNA mimetics
US9732342B2 · kind B2 · utility
2Cited by
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19Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 23, 2015 |
| Grant date | Aug 15, 2017 |
| Priority date | — |
| Expiry date | Jun 23, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates generally to segmented oligonucleotides capable of modulating gene expression. Specifically, the instant invention relates to segmented microRNA (miRNA) oligonucleotides, including segmented miRNA precursors and segmented pre-microRNAs. The invention also relates to compositions comprising such segmented oligonucleotides, as well as to methods of making and using such oligonucleotides for diagnosis and treatment of diseases associated or causally linked to aberrant levels or activities of gene expression, including aberrant levels of coding and/or non-coding RNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.