Formulations of deoxycholic acid and salts thereof
US9737549B2 · kind B2 · utility
3Cited by
66References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 26, 2013 |
| Grant date | Aug 22, 2017 |
| Priority date | — |
| Expiry date | Nov 26, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.