Nucleic acid particles, methods and use thereof
US9737557B2 · kind B2 · utility
6Cited by
82References
51Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 28, 2015 |
| Grant date | Aug 22, 2017 |
| Priority date | — |
| Expiry date | Jul 28, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6844
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides, among other things, a particle which includes a core comprised of self-assembled one or more nucleic acid molecules, the core being characterized by an ability to adopt at least two configurations: a first configuration having a first greatest dimension greater than 2 μm and; a second configuration having a second greatest dimension less than 500 nm, wherein addition of a film coating converts the core from its first configuration to its second configuration. Methods of making and using of provided particles are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.