Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions
US9738581B2 · kind B2 · utility
1Cited by
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5Claims
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Key dates
| Filing date | Nov 15, 2016 |
| Grant date | Aug 22, 2017 |
| Priority date | — |
| Expiry date | Nov 15, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A polyphenol derivative of the stilbenoid family, namely trans-3,5,4′-trihydroxybibenzyl, also known as dihydro-resveratrol, is disclosed as a remedial agent. In particular, the usage of dihydro-resveratrol as an anti-fibrotic agent in suppressing the activation of pancreatic stellate cells (PSCs) is presented. One embodiment also relates to the management of pancreatic fibrosis, which is often accompanied with chronic pancreatitis and desmoplastic reaction of pancreatic cancer. Another embodiment has applications in preventing or alleviating or treating pancreatic cancer or pancreatogenic diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.