Patent · US Active

Therapeutically active compounds and their methods of use

US9738625B2 · kind B2 · utility

11Cited by
2References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 1, 2014
Grant dateAug 22, 2017
Priority date
Expiry dateAug 1, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided are isocitrate dehydrogenase 2 (IDH2) inhibitor compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein. Also provided are polymorphic forms of the IDH2 inhibitor compounds characterized by X Ray powder diffraction patterns, having improved physicochemical properties that influence in vivo dissolution rate for formulation purposes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.