Patent · US Active

Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters

US9738663B2 · kind B2 · utility

0Cited by

1References

21Claims

0Family size

Assignee

EUTICALS SPA · IT

Inventors

Michael Nonnenmacher · Leimen, DE
Torsten Busch · Frankfurt am Main, DE

Key dates

Filing date	Apr 30, 2014
Grant date	Aug 22, 2017
Priority date	—
Expiry date	Apr 30, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F5/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters thereof of formula (I) in high yield. The claimed process uses diarylketal formula (V) to generate an arylbromide of formula (III) in which the amino-group is protected as bisarylmethylidenimino-group, which is then transformed into a formula (I) compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.